The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam
نویسندگان
چکیده
منابع مشابه
A role of the SAM domain in EphA2 receptor activation
Among the 20 subfamilies of protein receptor tyrosine kinases (RTKs), Eph receptors are unique in possessing a sterile alpha motif (SAM domain) at their C-terminal ends. However, the functions of SAM domains in Eph receptors remain elusive. Here we report on a combined cell biology and quantitative fluorescence study to investigate the role of the SAM domain in EphA2 function. We observed eleva...
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ژورنال
عنوان ژورنال: BMC Structural Biology
سال: 2009
ISSN: 1472-6807
DOI: 10.1186/1472-6807-9-59